James R. McCarthy

Stereospecific method to (E) and (Z) terminal fluoroolefins and its application to the synthesis of 2'-deoxy-2'-fluoromethylenenucleosides as potential inhibitors of ribonucleoside diphosphate reductase

James R. McCarthy, Donald P. Matthews, David M. Stemerick et al. · Journal of the American Chemical Society · 1991 · 195 citations

Life Sciences, Biochemistry, Chemistry +8

A new method for the synthesis of ketones: The palladium-catalyzed cross-coupling of acid chlorides with arylboronic acids

Mustapha Haddach, James R. McCarthy · Tetrahedron Letters · 1999 · 173 citations

Natural Sciences, Chemistry, Catalysis +9

Terminal difluoro olefin analogs of squalene are time-dependent inhibitors of squalene epoxidase

William R. Moore, Gerald L. Schatzman, Esa T. Jarvi et al. · Journal of the American Chemical Society · 1992 · 138 citations

Medicine, Chemistry, Pharmacology +7

Design and Synthesis of a Series of Non-Peptide High-Affinity Human Corticotropin-Releasing Factor₁ Receptor Antagonists

Chen Chen, Raymond Dagnino, Errol B. De Souza et al. · Journal of Medicinal Chemistry · 1996 · 137 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +7

Stereospecific synthesis of 1-fluoro olefins via (fluorovinyl)stannanes and an unequivocal NMR method for the assignment of fluoro olefin geometry

James R. McCarthy, Edward W. Huber, Tieu-Binh Le et al. · Tetrahedron · 1996 · 119 citations

Natural Sciences, Chemistry, Organic Chemistry +4