Tsuyoshi Yokoi

Near Completely Humanized Liver in Mice Shows Human-Type Metabolic Responses to Drugs

Chise Tateno, Yasumi Yoshizane, Naomi Saito et al. · American Journal Of Pathology · 2004 · 545 citations

Medicine, Pharmacokinetics, Pharmacology +12

Role of human cytochrome P4502A6 in C-oxidation of nicotine.

Masatoshi Nakajima, Takahiko Yamamoto, K Nunoya et al. · Drug Metabolism and Disposition · 1996 · 421 citations

Medicine, Biochemistry, Pharmacology +15

MicroRNA Regulates the Expression of Human Cytochrome P450 1B1

Yuki Tsuchiya, Miki Nakajima, Shingo Takagi et al. · Cancer Research · 2006 · 404 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Genetic Polymorphism in the 5'-Flanking Region of HumanCYP1A2 Gene: Effect on the CYP1A2 Inducibility in Humans

Mitsutoshi Nakajima, Tsuyoshi Yokoi, Mayumi Mizutani et al. · The Journal of Biochemistry · 1999 · 347 citations

Medicine, Molecular Genetics, Pharmacology +12

Involvement of beta-glucuronidase in intestinal microflora in the intestinal toxicity of the antitumor camptothecin derivative irinotecan hydrochloride (CPT-11) in rats.

Kiyoshi Takasuna, Takehiro Hagiwara, Masaaki Hirohashi et al. · PubMed · 1996 · 338 citations

Medicine, Pharmacology, Toxicology +17