Takehiro Hagiwara

Involvement of beta-glucuronidase in intestinal microflora in the intestinal toxicity of the antitumor camptothecin derivative irinotecan hydrochloride (CPT-11) in rats.

Kiyoshi Takasuna, Takehiro Hagiwara, Masaaki Hirohashi et al. · PubMed · 1996 · 338 citations

Medicine, Pharmacology, Toxicology +17

Inhibition of intestinal microflora β-glucuronidase modifies the distribution of the active metabolite of the antitumor agent, irinotecan hydrochloride (CPT-11) in rats

Kiyoshi Takasuna, Takehiro Hagiwara, Masaaki Hirohashi et al. · Cancer Chemotherapy and Pharmacology · 1998 · 116 citations

Medicine, Pharmacokinetics, Pharmacology +12

Protective Effects of <i>Kampo</i> Medicines and Baicalin against Intestinal Toxicity of a New Anticancer Camptothecin Derivative, Irinotecan Hydrochloride (CPT‐11), in Rats

Kiyoshi Takasuna, Yoshio Kasai, Yutaka Kitano et al. · Japanese Journal of Cancer Research · 1995 · 97 citations

Medicine, Pharmacology, Toxicology +11

In vivo experimental approach for the risk assessment of fluoroquinolone antibacterial agents-induced long QT syndrome

Katsuyoshi Chiba, Atsushi Sugiyama, Takehiro Hagiwara et al. · European Journal of Pharmacology · 2004 · 44 citations

Pharmacy, Pharmacokinetics, Pharmacology +13

A Comparative Study of the Fluoroquinolone Antibacterial Agents on the Action Potential Duration in Guinea Pig Ventricular Myocardia.

Takehiro Hagiwara, Sumie Satoh, Yoshio Kasai et al. · The Japanese Journal of Pharmacology · 2001 · 42 citations · Full text

Medicine, Pharmacology, Antimicrobial Pharmacology +12