Paul Rowland

A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response

Laurens Kruidenier, Chun‐wa Chung, Zhongjun Cheng et al. · Nature · 2012 · 958 citations · Full text

Life Sciences, Cell Biology, Immunology +14

Crystal Structure of Human Cytochrome P450 2D6

Paul Rowland, Frank E. Blaney, Martin G. Smyth et al. · Journal of Biological Chemistry · 2005 · 435 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition

Susan Wyllie, Stephen Brand, Michael G. Thomas et al. · Proceedings of the National Academy of Sciences · 2019 · 173 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Kynurenine-3-monooxygenase inhibition prevents multiple organ failure in rodent models of acute pancreatitis

Damian J. Mole, Scott P. Webster, Iain Uings et al. · Nature Medicine · 2016 · 160 citations · Full text

Medicine, Biochemistry, Pharmacology +8

Optimization of Novel Indazoles as Highly Potent and Selective Inhibitors of Phosphoinositide 3-Kinase δ for the Treatment of Respiratory Disease

Kenneth Down, Augustin Amour, Angela M. Deakin et al. · Journal of Medicinal Chemistry · 2015 · 132 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17