A. Yasemin Göksenin

Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers

Adam Shlien, Brittany Campbell, Richard de Borja et al. · Nature Genetics · 2015 · 372 citations · Full text

Genome Instability, Somatic Variant, Somatic Mutations +9

Exonuclease mutations in DNA polymerase epsilon reveal replication strand specific mutation patterns and human origins of replication

Eve Shinbrot, Erin E. Henninger, Nils Weinhold et al. · Genome Research · 2014 · 288 citations · Full text

Exonuclease Mutations, Genetics, Dna Analysis +21

Human DNA Polymerase ϵ Is Able to Efficiently Extend from Multiple Consecutive Ribonucleotides

A. Yasemin Göksenin, Walter J. Zahurancik, Kimberly G. LeCompte et al. · Journal of Biological Chemistry · 2012 · 60 citations · Full text

Genetics, Molecular Biology, Molecular Genetics +16

Explosive mutation accumulation triggered by heterozygous human Pol ε proofreading-deficiency is driven by suppression of mismatch repair

Karl P. Hodel, Richard de Borja, Erin E. Henninger et al. · eLife · 2018 · 39 citations · Full text

Engineering, Cancer Pathology, Genetics +19

Human Pol ɛ-dependent replication errors and the influence of mismatch repair on their correction

Anderson Ayuk Agbor, A. Yasemin Göksenin, Kimberly G. LeCompte et al. · DNA repair · 2013 · 21 citations · Full text

Genome Instability, Genetics, Dna Replication +6