Concepedia

Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers

Adam Shlien, Brittany Campbell, Richard de Borja, Ludmil B. Alexandrov, Daniele Merico, David C. Wedge, Peter Van Loo, Patrick Tarpey, Paul Coupland, Sam Behjati,

Nature Genetics · 2015 · 381 citations · 25 references

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25

Fast and accurate short read alignment with Burrows–Wheeler transform

Heng Li, Richard Durbin · Bioinformatics · 2009 · 62.8K citations · Full text

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The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

Aaron McKenna, Matthew G. Hanna, Eric Banks et al. · Genome Research · 2010 · 30K citations · Full text

, , +17

Signatures of mutational processes in human cancer

Ludmil B. Alexandrov, Serena Nik‐Zainal, David C. Wedge et al. · Nature · 2013 · 10.1K citations · Full text

, , +14

Comprehensive molecular characterization of human colon and rectal cancer

Nature · 2012 · 8.7K citations · Full text

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Integrated genomic characterization of endometrial carcinoma

Nature · 2013 · 5.8K citations · Full text

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