Yajing Yang

Discovery of a Potent, Selective, and Orally Bioavailable c-Met Inhibitor: 1-(2-Hydroxy-2-methylpropyl)-<i>N</i>-(5-(7-methoxyquinolin-4-yloxy)pyridin-2-yl)-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1<i>H</i>-pyrazole-4-carboxamide (AMG 458)

Longbin Liu, Aaron Siegmund, Ning Xi et al. · Journal of Medicinal Chemistry · 2008 · 95 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

Design, Synthesis, and Biological Evaluation of Potent c-Met Inhibitors

Noel D. D’Angelo, Steven F. Bellon, Shon K. Booker et al. · Journal of Medicinal Chemistry · 2008 · 90 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Antidiabetic-activity sulfated polysaccharide from Chaetomorpha linum: Characteristics of its structure and effects on oxidative stress and mitochondrial function

Ling Qin, Yajing Yang, Jiejie Hao et al. · International Journal of Biological Macromolecules · 2022 · 28 citations

Pharmacy, Biochemistry, Pharmacology +16

A Cross-Species Reactive TIGIT-Blocking Antibody Fc Dependently Confers Potent Antitumor Effects

Fang Yang, Linlin Zhao, Zhizhong Wei et al. · The Journal of Immunology · 2020 · 25 citations

Life Sciences, Immunology, Oncology +17

Discovery of AMG 193, an MTA-Cooperative PRMT5 Inhibitor for the Treatment of <i>MTAP</i>-Deleted Cancers

Liping H. Pettus, Matthew P. Bourbeau, Nuria Tamayo et al. · Journal of Medicinal Chemistry · 2025 · 23 citations

Medicine, Oncology, Pharmacology +10