Lois K. Chenard - Concepedia

Author

Lois K. Chenard

Pfizer (United States)

Also Known As

L. K. CHENARD, Lois Chenard, Lois K. Chenard, Lois Konicki Chenard

Publications

358

Citations

H-Index

Concepts

All Affiliations

Pfizer (United States)

About

Lois K. Chenard is an author at Pfizer (United States) specializing in drug discovery, medicine, and pharmacology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	3	3	88
2	Natural Sciences	2	2	74
3	Biochemistry	2	2	66
4	Engineering	1	1	12
5	Social Sciences	1	1	22

Lois K. Chenard

Publications

341

Citations

H-Index

Page 1

	Year	Citations
Identification of a Brain Penetrant PDE9A Inhibitor Utilizing Prospective Design and Chemical Enablement as a Rapid Lead Optimization Strategy Patrick R. Verhoest, Caroline Proulx-LaFrance, Michael L. Corman, Journal of Medicinal Chemistry	2009	65
3‘-Aminoadenosine-5‘-uronamides: Discovery of the First Highly Selective Agonist at the Human Adenosine A <sub>3</sub> Receptor Michael P. DeNinno, Hiroko Masamune, Lois K. Chenard, Journal of Medicinal Chemistry	2002	59
Use of Structure-Based Design to Discover a Potent, Selective, In Vivo Active Phosphodiesterase 10A Inhibitor Lead Series for the Treatment of Schizophrenia Christopher J. Helal, Zhijun Kang, Xinjun Hou, Journal of Medicinal Chemistry Combinatorial ChemistryDrug TargetMolecular BiologyPharmacotherapyChemical Biology	2011	52
Discovery and Preclinical Characterization of 1-Methyl-3-(4-methylpyridin-3-yl)-6-(pyridin-2-ylmethoxy)-1 <i>H</i> -pyrazolo-[3,4- <i>b</i> ]pyrazine (PF470): A Highly Potent, Selective, and Efficacious Metabotropic Glutamate Receptor 5 (mGluR5) Negative Allosteric Modulator Lei Zhang, Gayatri Balan, Gabriela Barreiro, Journal of Medicinal Chemistry	2014	51
Design and optimization of selective azaindole amide M1 positive allosteric modulators Jennifer E. Davoren, Steven V. O’Neil, Dennis P. Anderson, Bioorganic & Medicinal Chemistry Letters	2015	44
Discovery of a novel Kv7 channel opener as a treatment for epilepsy Jennifer E. Davoren, Michelle M. Claffey, Sheri L. Snow, Bioorganic & Medicinal Chemistry Letters Neuromodulation (Medicine)NeurophysiologyNeuromodulation TherapiesIon ChannelsNeuroscience	2015	22
Selective Access to Heterocyclic Sulfonamides and Sulfonyl Fluorides via a Parallel Medicinal Chemistry Enabled Method Joseph W. Tucker, Lois K. Chenard, Joseph M. Young ACS Combinatorial Science Combinatorial ChemistryRapid AccessParallel Medicinal ChemistryOrganic ChemistryChemistry	2015	22
The synthesis of highly potent, selective, and water-soluble agonists at the human adenosine A3 receptor Michael P. DeNinno, Hiroko Masamune, Lois K. Chenard, Bioorganic & Medicinal Chemistry Letters Molecular PharmacologyBiochemistryFunctional SelectivityMedicineG Protein-coupled Receptor	2006	14
Mechanistic aspects of photocycloaddition chemistry. An interesting relationship between substituent effects on 1,4-biradical closure-to-cleavage ratios and photocycloaddition regioselectivity T. G. Savino, Lois K. Chenard, John S. Swenton Tetrahedron Letters EngineeringPhotoredox ProcessPhotochemistryPhotocycloaddition ChemistryMechanistic Photochemistry	1983	12

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