Longitudinal analysis of murine steatohepatitis model induced by chronic exposure to high‐fat diet

Makoto Ito, Jun Suzuki, Shigeharu Tsujioka, +8

Hepatology Research

Chronic intracerebroventricular infusion of MCH causes obesity in mice

Akira Gomori, Akane Ishihara, Masahiko Ito, +9

American Journal of Physiology-Endocrinology and Metabolism

NutritionMetabolic DisorderGastrointestinal Peptide HormoneObesityMetabolic Syndrome +16

Characterization of MCH-mediated obesity in mice

Masahiko Ito, Akira Gomori, Akane Ishihara, +10

American Journal of Physiology-Endocrinology and Metabolism

ObesityMetabolic SyndromeAnimal PhysiologyEnergy HomeostasisGastrointestinal Peptide Hormone +13

TAS-116, a Highly Selective Inhibitor of Heat Shock Protein 90α and β, Demonstrates Potent Antitumor Activity and Minimal Ocular Toxicity in Preclinical Models

Shuichi Ohkubo, Yasuo Kodama, Hiromi Muraoka, +10

Molecular Cancer Therapeutics

Antiobesity Effect of a Melanin-Concentrating Hormone 1 Receptor Antagonist in Diet-Induced Obese Mice

Satoshi Mashiko, Akane Ishihara, Akira Gomori, +10

Endocrinology

NutritionReceptor AntagonistGastrointestinal Peptide HormoneObesityMetabolic Syndrome +15

A neuropeptide Y Y5 antagonist selectively ameliorates body weight gain and associated parameters in diet-induced obese mice

Akane Ishihara, Akio Kanatani, Satoshi Mashiko, +21

Proceedings of the National Academy of Sciences

Associated ParametersCaloric RestrictionGastrointestinal Peptide HormoneNpy ReceptorsObesity +17

(9<i>S</i>)-9-(2-Hydroxy-4,4-dimethyl-6-oxo-1-cyclohexen-1-yl)-3,3-dimethyl-2,3,4,9-tetrahydro-1<i>H</i>-xanthen-1-one, a Selective and Orally Active Neuropeptide Y Y5 Receptor Antagonist

Nagaaki Sato, Makoto Jitsuoka, Takunobu Shibata, +12

Journal of Medicinal Chemistry

Synergistic interaction between neuropeptide Y1 and Y5 receptor pathways in regulation of energy homeostasis

Satoshi Mashiko, Ryuichi Moriya, Akane Ishihara, +8

European Journal of Pharmacology

Energy HomeostasisSignal TransductionNeuropeptide Y1Y5 Receptor PathwaysPhysiology +11

A Pair-Feeding Study Reveals That a Y5 Antagonist Causes Weight Loss in Diet-Induced Obese Mice by Modulating Food Intake and Energy Expenditure

Satoshi Mashiko, Akane Ishihara, Hisashi Iwaasa, +12

Molecular Pharmacology

Mechanism of the anti‐obesity effects induced by a novel Melanin‐concentrating hormone 1‐receptor antagonist in mice

Masahiko Ito, Akane Ishihara, Akira Gomori, +12

British Journal of Pharmacology