Hiromi Muraoka

TAS-116, a Highly Selective Inhibitor of Heat Shock Protein 90α and β, Demonstrates Potent Antitumor Activity and Minimal Ocular Toxicity in Preclinical Models

Shuichi Ohkubo, Yasuo Kodama, Hiromi Muraoka et al. · Molecular Cancer Therapeutics · 2014 · 128 citations

Involvement of Multidrug Resistance-Associated Protein 2 in Intestinal Secretion of Grepafloxacin in Rats

Kazumasa Naruhashi, Ikumi Tamai, Natsuko Inoue et al. · Antimicrobial Agents and Chemotherapy · 2002 · 76 citations · Full text

TAS4464, A Highly Potent and Selective Inhibitor of NEDD8-Activating Enzyme, Suppresses Neddylation and Shows Antitumor Activity in Diverse Cancer Models

Chihoko Yoshimura, Hiromi Muraoka, Hiroaki Ochiiwa et al. · Molecular Cancer Therapeutics · 2019 · 65 citations

Discovery of 3-Ethyl-4-(3-isopropyl-4-(4-(1-methyl-1<i>H</i>-pyrazol-4-yl)-1<i>H</i>-imidazol-1-yl)-1<i>H</i>-pyrazolo[3,4-<i>b</i>]pyridin-1-yl)benzamide (TAS-116) as a Potent, Selective, and Orally Available HSP90 Inhibitor

Takao Uno, Yuichi Kawai, Satoshi Yamashita et al. · Journal of Medicinal Chemistry · 2018 · 55 citations · Full text

Active intestinal secretion of new quinolone antimicrobials and the partial contribution of P-glycoprotein

Kazumasa Naruhashi, Ikumi Tamai, Natsuko Inoue et al. · Journal of Pharmacy and Pharmacology · 2001 · 51 citations · Full text

Secretory-directed Transport, Immunology, Gastroenterology +19