Takao Uno

TAS6417, A Novel EGFR Inhibitor Targeting Exon 20 Insertion Mutations

Shinichi Hasako, Miki Terasaka, Naomi Abe et al. · Molecular Cancer Therapeutics · 2018 · 85 citations

Medicine, Oncology, Pharmacology +17

Structure–activity relationships of epolactaene derivatives: structural requirements for inhibition of Hsp60 chaperone activity

Yoko Nagumo, Hideaki Kakeya, Junichiro Yamaguchi et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 56 citations

Life Sciences, Biochemistry, Medicinal Chemistry +17

Discovery of 3-Ethyl-4-(3-isopropyl-4-(4-(1-methyl-1<i>H</i>-pyrazol-4-yl)-1<i>H</i>-imidazol-1-yl)-1<i>H</i>-pyrazolo[3,4-<i>b</i>]pyridin-1-yl)benzamide (TAS-116) as a Potent, Selective, and Orally Available HSP90 Inhibitor

Takao Uno, Yuichi Kawai, Satoshi Yamashita et al. · Journal of Medicinal Chemistry · 2018 · 55 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Determination by Asymmetric Total Synthesis of the Absolute Configuration of Lucilactaene, a Cell‐Cycle Inhibitor in p53‐Transfected Cancer Cells

Junichiro Yamaguchi, Hideaki Kakeya, Takao Uno et al. · Angewandte Chemie International Edition · 2005 · 35 citations

Medicine, Medicinal Chemistry, Oncology +13

Enantio- and Diastereoselective Total Synthesis of EI-1941−1, −2, and −3, Inhibitors of Interleukin-1β Converting Enzyme, and Biological Properties of Their Derivatives

Mitsuru Shoji, Takao Uno, Hideaki Kakeya et al. · The Journal of Organic Chemistry · 2005 · 24 citations

Pharmacy, Chemistry, Medicinal Chemistry +10