Bohdan Yaremko

Antitumor activity of SCH 66336, an orally bioavailable tricyclic inhibitor of farnesyl protein transferase, in human tumor xenograft models and wap-ras transgenic mice.

Ming Liu, Matthew Bryant, Jianping Chen et al. · PubMed · 1998 · 309 citations

Sch 66336, Chemoprevention Strategy, Farnesyl Protein Transferase +15

Inhibition of angiogenesis and tumor growth by SCH221153, a dual alpha(v)beta3 and alpha(v)beta5 integrin receptor antagonist.

C. Chandra Kumar, M Malkowski, Z Yin et al. · PubMed · 2001 · 174 citations

Molecular Pharmacology, Angiogenesis, Sch 221153 +13

The farnesyl protein transferase inhibitor SCH66336 synergizes with taxanes in vitro and enhances their antitumor activity in vivo

Bin Shi, Bohdan Yaremko, Gerald Hajian et al. · Cancer Chemotherapy and Pharmacology · 2000 · 112 citations

Tumor Biology, Antitumor Activity, Oncogenic Agent +7

Structure−Activity Relationship of 3-Substituted <i>N</i>-(Pyridinylacetyl)-4- (8-chloro-5,6-dihydro-11<i>H</i>-benzo[5,6]cyclohepta[1,2-<i>b</i>]pyridin-11-ylidene)- piperidine Inhibitors of Farnesyl-Protein Transferase:  Design and Synthesis of in Vivo Active Antitumor Compounds

F. George Njoroge, Bancha Vibulbhan, Dinananth F. Rane et al. · Journal of Medicinal Chemistry · 1997 · 52 citations · Full text

Analogue 38, Analogues 19, Pharmacotherapy +16

Biological activities of a chemically synthesized form of leukotriene E4

Ann F. Welton, Herman J. Crowley, Dave A. Miller et al. · Prostaglandins · 1981 · 47 citations

Bioorganic Chemistry, Biochemistry, Natural Sciences +6