Concepedia

Robert C. Orchard

RC

38

Publications

8.8K

Citations

28

H-Index

1980

Active since

Affiliations

Washington University in St. Louis(Current)

The University of Texas Southwestern Medical Center

Broad Institute

Yale University

Harvard University

Robert C. Orchard is an author at Washington University in St. Louis specializing in medicine, immunology, and pathogenesis.

Top concepts

MedicineImmunologyPathogenesisVirologyCell BiologyCell SignalingViral PathogenesisCardiologyAutophagyInflammation

Publications per year

1980–2023

38

Publications

38

Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9

John G. Doench, Nicolò Fusi, Meagan E. Sullender et al. · Nature Biotechnology · 2016 · 4.7K citations · Full text

Systems Biology, Off-target Effect, Natural Sciences +10

RETRACTED ARTICLE: Molecular characterization of LC3-associated phagocytosis reveals distinct roles for Rubicon, NOX2 and autophagy proteins

Jennifer Martinez, R. K. Subbarao Malireddi, Qun Lu et al. · Nature Cell Biology · 2015 · 770 citations · Full text

Inflammation, Cell Autophagy, Molecular Characterization +9

Genome-wide CRISPR Screens Reveal Host Factors Critical for SARS-CoV-2 Infection

Jin Wei, Mia Madel Alfajaro, Peter C. DeWeirdt et al. · Cell · 2020 · 572 citations · Full text

Sars-cov-2 Infection, Pathogenesis, Virology +8

RETRACTED ARTICLE: Noncanonical autophagy inhibits the autoinflammatory, lupus-like response to dying cells

Jennifer Martinez, Larissa D. Cunha, Sunmin Park et al. · Nature · 2016 · 384 citations · Full text

Apoptosis, Immunology, Cell Death +19

Discovery of a proteinaceous cellular receptor for a norovirus

Robert C. Orchard, Craig B. Wilen, John G. Doench et al. · Science · 2016 · 288 citations · Full text

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