Craig B. Wilen

Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9

John G. Doench, Nicolò Fusi, Meagan E. Sullender et al. · Nature Biotechnology · 2016 · 5K citations

Life Sciences, Biotechnology, Molecular Biology +13

Neuroinvasion of SARS-CoV-2 in human and mouse brain

Eric Song, Ce Zhang, Benjamin Israelow et al. · The Journal of Experimental Medicine · 2020 · 1K citations · Full text

Life Sciences, Infectious Diseases, Neuroscience +17

Genome-wide CRISPR Screens Reveal Host Factors Critical for SARS-CoV-2 Infection

Jin Wei, Mia Madel Alfajaro, Peter C. DeWeirdt et al. · Cell · 2020 · 583 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +12

Inflammasome activation in infected macrophages drives COVID-19 pathology

Esen Sefik, Rihao Qu, Caroline Junqueira et al. · Nature · 2022 · 533 citations · Full text

Veterinary Medicine, Immunology, Infectious Diseases +16

Altered Virome and Bacterial Microbiome in Human Immunodeficiency Virus-Associated Acquired Immunodeficiency Syndrome

Cynthia L. Monaco, David B. Gootenberg, Guoyan Zhao et al. · Cell Host & Microbe · 2016 · 442 citations · Full text

Life Sciences, Infectious Diseases, Microbiology +17