Jan Korábečný

Phosphatidylinositol 3-Kinase (PI3K) and Phosphatidylinositol 3-Kinase-Related Kinase (PIKK) Inhibitors: Importance of the Morpholine Ring

Martin Andrš, Jan Korábečný, Daniel Jun et al. · Journal of Medicinal Chemistry · 2014 · 151 citations · Full text

Life Sciences, Molecular Biology, Oncology +13

Multitarget Drug Design Strategy: Quinone–Tacrine Hybrids Designed To Block Amyloid-β Aggregation and To Exert Anticholinesterase and Antioxidant Effects

Eugenie Nepovimová, Elisa Uliassi, Jan Korábečný et al. · Journal of Medicinal Chemistry · 2014 · 150 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

Tacrine–Trolox Hybrids: A Novel Class of Centrally Active, Nonhepatotoxic Multi-Target-Directed Ligands Exerting Anticholinesterase and Antioxidant Activities with Low In Vivo Toxicity

Eugenie Nepovimová, Jan Korábečný, Rafael Doležal et al. · Journal of Medicinal Chemistry · 2015 · 129 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Synthesis and Biological Evaluation of Novel Tacrine Derivatives and Tacrine–Coumarin Hybrids as Cholinesterase Inhibitors

Slávka Hamuľaková, Ladislav Janovec, Martina Hrabinová et al. · Journal of Medicinal Chemistry · 2014 · 112 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Tacrine-resveratrol fused hybrids as multi-target-directed ligands against Alzheimer's disease

J Jerábek, Elisa Uliassi, Laura Guidotti et al. · European Journal of Medicinal Chemistry · 2016 · 110 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14