Frank M. Boeckler

Principles and Applications of Halogen Bonding in Medicinal Chemistry and Chemical Biology

Rainer Wilcken, Markus O. Zimmermann, Andreas Lange et al. · Journal of Medicinal Chemistry · 2012 · 1.3K citations · Full text

Halogenation, Molecular Recognition, Medicinal Chemistry +15

Targeted rescue of a destabilized mutant of p53 by an <i>in silico</i> screened drug

Frank M. Boeckler, Andreas C. Joerger, Gaurav Jaggi et al. · Proceedings of the National Academy of Sciences · 2008 · 368 citations · Full text

Crystal Structure, Drug Target, Biomolecular Structure Prediction +18

Halogen-Enriched Fragment Libraries as Leads for Drug Rescue of Mutant p53

Rainer Wilcken, Xiangrui Liu, Markus O. Zimmermann et al. · Journal of the American Chemical Society · 2012 · 229 citations · Full text

Molecular Biology, Chemical Biology, Mutant P53 +20

Evaluation and Optimization of Virtual Screening Workflows with DEKOIS 2.0 – A Public Library of Challenging Docking Benchmark Sets

Matthias R. Bauer, Tamer M. Ibrahim, Simon Vogel et al. · Journal of Chemical Information and Modeling · 2013 · 190 citations

Engineering, Hit Identification, Molecular Biology +19

Kinetic mechanism of p53 oncogenic mutant aggregation and its inhibition

Rainer Wilcken, GuoZhen Wang, Frank M. Boeckler et al. · Proceedings of the National Academy of Sciences · 2012 · 119 citations · Full text