Frank M. Boeckler - Concepedia

Author

Frank M. Boeckler

Also Known As

A.R. Fersht, Boeckler, F., Boeckler, Frank M., F. Boeckler, F. M. Boeckler, F.M. Boeckler, FM Boeckler, Frank Boeckler, Frank M Boeckler, Frank M. Boeckler

Publications

4.3K

Citations

H-Index

Concepts

All Affiliations

University of Tübingen Friedrich-Alexander-Universität Erlangen-Nürnberg Fischer (Germany)MRC Laboratory of Molecular Biology Kafrelsheikh University

About

Frank M. Boeckler is an author at University of Tübingen specializing in medicine, biochemistry, and drug discovery.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	22	28	1.8K
2	Biochemistry	21	25	2.9K
3	Natural Sciences	20	24	2.7K
4	Engineering	11	11	1.8K
5	Social Sciences	2	2	58

Frank M. Boeckler

Publications

4.1K

Citations

H-Index

Page 1

	Year	Citations
Principles and Applications of Halogen Bonding in Medicinal Chemistry and Chemical Biology Rainer Wilcken, Markus O. Zimmermann, Andreas Lange, Journal of Medicinal Chemistry HalogenationMolecular RecognitionMedicinal ChemistryHalogen BondingEngineering	2012	1.3K
Targeted rescue of a destabilized mutant of p53 by an <i>in silico</i> screened drug Frank M. Boeckler, Andreas C. Joerger, Gaurav Jaggi, Proceedings of the National Academy of Sciences Crystal StructureDrug TargetBiomolecular Structure PredictionMolecular BiologyTumor Biology	2008	368
Halogen-Enriched Fragment Libraries as Leads for Drug Rescue of Mutant p53 Rainer Wilcken, Xiangrui Liu, Markus O. Zimmermann, Journal of the American Chemical Society Molecular BiologyChemical BiologyMutant P53Medicinal ChemistryMolecular Characterization	2012	229
Evaluation and Optimization of Virtual Screening Workflows with DEKOIS 2.0 – A Public Library of Challenging Docking Benchmark Sets Matthias R. Bauer, Tamer M. Ibrahim, Simon Vogel, Journal of Chemical Information and Modeling EngineeringHit IdentificationMolecular BiologySoftware AnalysisA Public Library	2013	190
Kinetic mechanism of p53 oncogenic mutant aggregation and its inhibition Rainer Wilcken, GuoZhen Wang, Frank M. Boeckler, Proceedings of the National Academy of Sciences	2012	119
Using halogen bonds to address the protein backbone: a systematic evaluation Rainer Wilcken, Markus O. Zimmermann, Andreas Lange, Journal of Computer-Aided Molecular Design Protein ChemistryBiochemistryProtein AssemblyProtein FoldingHalogen Bonds	2012	100
DEKOIS: Demanding Evaluation Kits for Objective <i>in Silico</i> Screening — A Versatile Tool for Benchmarking Docking Programs and Scoring Functions Simon Vogel, Matthias R. Bauer, Frank M. Boeckler Journal of Chemical Information and Modeling EngineeringMachine LearningHit IdentificationBenchmarking Docking ProgramsSilico Screening	2011	88
Targeting the Gatekeeper MET146 of C-Jun N-Terminal Kinase 3 Induces a Bivalent Halogen/Chalcogen Bond Andreas Lange, Marcel Günther, Felix Michael Büttner, Journal of the American Chemical Society Gatekeeper Met146Molecular BiologyCell DeathChemical BiologyMolecular Pharmacology	2015	80
Tri- and Tetrasubstituted Pyrazole Derivates: Regioisomerism Switches Activity from p38MAP Kinase to Important Cancer Kinases Bassam Abu Thaher, Martina Arnsmann, Frank Totzke, Journal of Medicinal Chemistry	2011	73
Harnessing Fluorine–Sulfur Contacts and Multipolar Interactions for the Design of p53 Mutant Y220C Rescue Drugs Matthias R. Bauer, Rhiannon N. Jones, Matthias G. J. Baud, ACS Chemical Biology	2016	73

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