Matthias R. Bauer - Concepedia

Author

Matthias R. Bauer

Also Known As

Bauer, Matthias R., M Bauer, M. BAUER, M. Bauer, M.R. Bauer, Matthias Bauer, Matthias R Bauer, Matthias R. Bauer, Matthias R. Bauer

Publications

2.1K

Citations

H-Index

Concepts

All Affiliations

University of Tübingen MRC Laboratory of Molecular Biology Medical Research Council AstraZeneca (Sweden)Goethe University Frankfurt

About

Matthias R. Bauer is an author at University of Tübingen specializing in medicine, molecular docking, and molecular biology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	16	19	1.2K
2	Natural Sciences	8	8	449
3	Biochemistry	8	8	616
4	Engineering	6	6	432
5	Biomolecular Engineering	5	5	188

Matthias R. Bauer

Publications

1.6K

Citations

H-Index

Page 1

	Year	Citations
Evaluation and Optimization of Virtual Screening Workflows with DEKOIS 2.0 – A Public Library of Challenging Docking Benchmark Sets Matthias R. Bauer, Tamer M. Ibrahim, Simon Vogel, Journal of Chemical Information and Modeling EngineeringHit IdentificationMolecular BiologySoftware AnalysisA Public Library	2013	190
Electrostatic Complementarity as a Fast and Effective Tool to Optimize Binding and Selectivity of Protein–Ligand Complexes Matthias R. Bauer, Mark Mackey Journal of Medicinal Chemistry BiochemistryNatural SciencesMedicineSmall MoleculesProtein–ligand Complexes	2019	177
2-Sulfonylpyrimidines: Mild alkylating agents with anticancer activity toward p53-compromised cells Matthias R. Bauer, Andreas C. Joerger, Alan R. Fersht Proceedings of the National Academy of Sciences Chemoprevention StrategyP53 DependentCancer BiologyTumor BiologyUnstable P53	2016	115
DEKOIS: Demanding Evaluation Kits for Objective <i>in Silico</i> Screening — A Versatile Tool for Benchmarking Docking Programs and Scoring Functions Simon Vogel, Matthias R. Bauer, Frank M. Boeckler Journal of Chemical Information and Modeling EngineeringMachine LearningHit IdentificationBenchmarking Docking ProgramsSilico Screening	2011	88
Aminobenzothiazole derivatives stabilize the thermolabile p53 cancer mutant Y220C and show anticancer activity in p53-Y220C cell lines Matthias G. J. Baud, Matthias R. Bauer, Lorena Verduci, European Journal of Medicinal Chemistry	2018	85
A Structure-Guided Molecular Chaperone Approach for Restoring the Transcriptional Activity of the p53 Cancer Mutant Y220C Matthias R. Bauer, Rhiannon N. Jones, Raysa Khan Tareque, Future Medicinal Chemistry	2019	79
Targeting Cavity-Creating p53 Cancer Mutations with Small-Molecule Stabilizers: the Y220X Paradigm Matthias R. Bauer, Andreas Krämer, Giovanni Settanni, ACS Chemical Biology Y220x ParadigmProtein AssemblyBiomolecular Structure PredictionY220c MutantMolecular Biology	2020	74
Harnessing Fluorine–Sulfur Contacts and Multipolar Interactions for the Design of p53 Mutant Y220C Rescue Drugs Matthias R. Bauer, Rhiannon N. Jones, Matthias G. J. Baud, ACS Chemical Biology	2016	73
DockStream: a docking wrapper to enhance de novo molecular design Jeff Guo, Jon Paul Janet, Matthias R. Bauer, Journal of Cheminformatics Drug TargetEngineeringMolecular BiologyMolecular DesignReinvent Agent	2021	71
Mutant p53 as a therapeutic target for the treatment of triple-negative breast cancer: Preclinical investigation with the anti-p53 drug, PK11007 Naoise C. Synnott, Matthias R. Bauer, Stephen F. Madden, Cancer Letters Mutant P53Breast OncologyMedicineAnti-p53 DrugBreast Cancer	2017	69

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