Toru Okamoto

The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism

James M. Murphy, Peter E. Czabotar, Joanne M. Hildebrand et al. · Immunity · 2013 · 1.2K citations · Full text

Protein Function, Signal Transduction, Medicine +14

Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7

Ingrid E. Wertz, Saritha Kusam, Cynthia Lam et al. · Nature · 2011 · 806 citations

Protein Function, Medicine, Immune Checkpoint Inhibitor +9

A Cluster of Interferon-γ-Inducible p65 GTPases Plays a Critical Role in Host Defense against Toxoplasma gondii

Masahiro Yamamoto, Megumi Okuyama, Ji Su et al. · Immunity · 2012 · 330 citations · Full text

Host Response, Parasitic Protozoa, Pathogenesis +9

An infectivity-enhancing site on the SARS-CoV-2 spike protein targeted by antibodies

Yafei Liu, Wai Tuck Soh, Jun-ichi Kishikawa et al. · Cell · 2021 · 285 citations · Full text

Vaccine Target, Viral Pathogenesis, Immunology +7

Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signaling

Masahiro Yamamoto, Toru Okamoto, Kiyoshi Takeda et al. · Nature Immunology · 2006 · 268 citations

Molecular Immunology, Signal Transduction, Immune Receptor +9