An infectivity-enhancing site on the SARS-CoV-2 spike protein targeted by antibodies

Yafei Liu, Wai Tuck Soh, Jun-ichi Kishikawa, +34

Cell

Vaccine TargetViral PathogenesisImmunologyInfectivity-enhancing SiteVirology +5

Patterns of IgE sensitization in house dust mite‐allergic patients: implications for allergen immunotherapy

Thierry Batard, Véronique Baron‐Bodo, Armelle Martelet, +15

Allergy

The N-terminal domain of spike glycoprotein mediates SARS-CoV-2 infection by associating with L-SIGN and DC-SIGN

Wai Tuck Soh, Yafei Liu, Emi E. Nakayama, +6

Humoral ResponseViral PathogenesisImmunologyViral Structural ProteinVirus Structure +14

Distinct Roles of Catalytic Cysteine and Histidine in the Protease and Ligase Mechanisms of Human Legumain As Revealed by DFT-Based QM/MM Simulations

Brigitta Elsässer, Florian B. Zauner, Johann Messner, +3

ACS Catalysis

Protein AssemblyMolecular BiologyCatalytic CysteinePeptide ScienceHuman Legumain +15

Multiple roles of Bet v 1 ligands in allergen stabilization and modulation of endosomal protease activity

Wai Tuck Soh, Lorenz Aglas, Geoffrey A. Mueller, +12

Allergy

Synthesis and biological evaluation of potential inhibitors of the cysteine proteases cruzain and rhodesain designed by molecular simplification

Saulo Fehelberg Pinto Braga, Luan Carvalho Martins, Elany Barbosa da Silva, +7

Bioorganic & Medicinal Chemistry

BiochemistryMedicineMolecular SimplificationNatural SciencesPotential Inhibitors +6

The House Dust Mite Major Allergen Der p 23 Displays O-Glycan-Independent IgE Reactivities but No Chitin-Binding Activity

Wai Tuck Soh, Maxime Le Mignon, Narissara Suratannon, +10

International Archives of Allergy and Immunology

The minor house dust mite allergen Der p 13 is a fatty acid‐binding protein and an activator of a TLR2‐mediated innate immune response

Pattraporn Satitsuksanoa, Malcolm W. Kennedy, Dimitri Gilis, +12

Allergy

Structural and functional studies of Arabidopsis thaliana legumain beta reveal isoform specific mechanisms of activation and substrate recognition

Elfriede Dall, Florian B. Zauner, Wai Tuck Soh, +5

Journal of Biological Chemistry

Distinct epitope structures of defensin‐like proteins linked to proline‐rich regions give rise to differences in their allergenic activity

Isabel Pablos, Stephanie Pauline Eichhorn, Yoan Machado, +12

Allergy