Xiaoling Cockcroft

4-[3-(4-Cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorobenzyl]-2<i>H</i>-phthalazin-1-one: A Novel Bioavailable Inhibitor of Poly(ADP-ribose) Polymerase-1

Keith Menear, Claire Adcock, Robert Boulter et al. · Journal of Medicinal Chemistry · 2008 · 586 citations · Full text

Medicine, Oncology, Pharmacology +16

Improved ATM kinase inhibitor KU-60019 radiosensitizes glioma cells, compromises insulin, AKT and ERK prosurvival signaling, and inhibits migration and invasion

Sarah E. Golding, Elizabeth Rosenberg, Nicholas C.K. Valerie et al. · Molecular Cancer Therapeutics · 2009 · 389 citations · Full text

Medicine, Cancer Biology, Oncology +14

Structure-Based Design of an in Vivo Active Selective BRD9 Inhibitor

Laetitia J. Martin, Manfred Koegl, Gerd Bader et al. · Journal of Medicinal Chemistry · 2016 · 224 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +13

Discovery of Potent Chromen-4-one Inhibitors of the DNA-Dependent Protein Kinase (DNA-PK) Using a Small-Molecule Library Approach

Ian R. Hardcastle, Xiaoling Cockcroft, Nicola J. Curtin et al. · Journal of Medicinal Chemistry · 2005 · 170 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Fragment-based discovery of a chemical probe for the PWWP1 domain of NSD3

Jark Böttcher, David Dilworth, Ulrich Reiser et al. · Nature Chemical Biology · 2019 · 103 citations

Pharmacy, Chemistry, Molecular Biology +16