Virginie Penard‐Lacronique

A TEL-JAK2 Fusion Protein with Constitutive Kinase Activity in Human Leukemia

Virginie Penard‐Lacronique, Anthony Boureux, Véronique Della Valle et al. · Science · 1997 · 790 citations

Immunology, Human Leukemia, Tumor Biology +16

Targeted Inhibition of Mutant IDH2 in Leukemia Cells Induces Cellular Differentiation

Fang Wang, Jeremy Travins, Byron DeLaBarre et al. · Science · 2013 · 789 citations

AG-221, a First-in-Class Therapy Targeting Acute Myeloid Leukemia Harboring Oncogenic <i>IDH2</i> Mutations

Katharine Yen, Jeremy Travins, Fang Wang et al. · Cancer Discovery · 2017 · 444 citations · Full text

Discovery of AG-120 (Ivosidenib): A First-in-Class Mutant IDH1 Inhibitor for the Treatment of IDH1 Mutant Cancers

Janeta Popovici-Müller, René M. Lemieux, Erin Artin et al. · ACS Medicinal Chemistry Letters · 2018 · 422 citations · Full text

Idh1 Mutant Cancers, Somatic Point Mutations, Somatic Variant +14

Bcl–2 protects from lethal hepatic apoptosis induced by an ant–Fas antibody in mice

Virginie Penard‐Lacronique, Alexandre Mignon, Monique Fabrè et al. · Nature Medicine · 1996 · 366 citations

Inflammation, Molecular Immunology, Liver Physiology +13