Andrew Olaharski

Discovery of AG-120 (Ivosidenib): A First-in-Class Mutant IDH1 Inhibitor for the Treatment of IDH1 Mutant Cancers

Janeta Popovici-Müller, René M. Lemieux, Erin Artin et al. · ACS Medicinal Chemistry Letters · 2018 · 422 citations · Full text

Idh1 Mutant Cancers, Somatic Point Mutations, Somatic Variant +14

Tetraploidy and chromosomal instability are early events during cervical carcinogenesis

Andrew Olaharski, Rita Sotelo, Gilberto Solorza-Luna et al. · Carcinogenesis · 2005 · 255 citations · Full text

Precancerous Lesions, Cytogenetics, Chromosomal Instability +16

Interlaboratory Evaluation of Genomic Signatures for Predicting Carcinogenicity in the Rat

Mark R. Fielden, Alex Nie, Michael McMillian et al. · Toxicological Sciences · 2008 · 92 citations · Full text

Leucine-Rich Repeat Kinase 2 (LRRK2)-Deficient Rats Exhibit Renal Tubule Injury and Perturbations in Metabolic and Immunological Homeostasis

Daniel Ness, Zhao Ren, Shyra J. Gardai et al. · PLoS ONE · 2013 · 90 citations · Full text

The Flavoring Agent Dihydrocoumarin Reverses Epigenetic Silencing and Inhibits Sirtuin Deacetylases

Andrew Olaharski, Jasper Rine, Brett Marshall et al. · PLoS Genetics · 2005 · 90 citations · Full text

Chemoprevention Strategy, Apoptosis, Cell Death +16