Predictive toxicogenomics approaches reveal underlying molecular mechanisms of nongenotoxic carcinogenicity

Alex Nie, Michael McMillian, J. Brandon Parker, +8

Molecular Carcinogenesis

Interlaboratory Evaluation of Genomic Signatures for Predicting Carcinogenicity in the Rat

Mark R. Fielden, Alex Nie, Michael McMillian, +32

Toxicological Sciences

A gene expression signature for oxidant stress/reactive metabolites in rat liver

Michael McMillian, Alex Nie, J. Brandon Parker, +10

Biochemical Pharmacology

Gene Expression SignatureHepatologyBiochemistryLiver PhysiologyPhysiology +12

Evaluation of Felbamate and Other Antiepileptic Drug Toxicity Potential Based on Hepatic Protein Covalent Binding and Gene Expression

Angelique M. Leone, L. Mark Kao, Michael McMillian, +7

Chemical Research in Toxicology

Valproic AcidPharmacological StudyBiochemistryMedicineDrug Discovery +12

Inverse gene expression patterns for macrophage activating hepatotoxicants and peroxisome proliferators in rat liver

Michael McMillian, Alex Nie, J. Brandon Parker, +9

Biochemical Pharmacology

ImmunologyPathologyCell DeathOxidative StressInflammation +16

Oxidative stress/reactive metabolite gene expression signature in rat liver detects idiosyncratic hepatotoxicants

Angelique M. Leone, Alex Nie, J. Brandon Parker, +9

Toxicology and Applied Pharmacology

PathologyIdiosyncratic HepatotoxicantsRedox BiologyToxicological MechanismOxidative Stress +14

On Methods for Gene Function Scoring as a Means of Facilitating the Interpretation of Microarray Results

N. R. Srinivasa Raghavan, Dhammika Amaratunga, Javier Cabrera, +3

Journal of Computational Biology

GeneticsGenetic EpidemiologyGene Expression ProfilingGenetic AnalysisGene Function Scoring +19

CLASS PREDICTION IN TOXICOGENOMICS

Nandini Raghavan, Dhammika Amaratunga, Alex Nie, +1

Journal of Biopharmaceutical Statistics

PathologyToxicogenomics StudyToxicological MechanismToxicologyBiostatistics +17

Characterization of genetic alteration patterns in human esophageal squamous cell carcinoma using selected microsatellite markers spanning multiple loci

Yuyang Cai, Chi So, Alex Nie, +6

International Journal of Oncology

Esophageal CancerGeneticsPathologyEscc CasesTumor Biology +15

Hepatic expression of heme oxygenase-1 and antioxidant response element-mediated genes following administration of ethinyl estradiol to rats

Lisa A. Morio, Anna Leone, Satin G. Sawant, +6

Toxicology and Applied Pharmacology

Health SciencesBiochemistryHeme HomeostasisMedicineLiver Physiology +11