Interfaces of Malignant and Immunologic Clonal Dynamics in Ovarian Cancer

Allen W. Zhang, Andrew McPherson, Katy Milne, +42

Cell

Malignant DiseaseTumor HeterogeneityMedicineGynecologyRadiation Oncology +7

Ovarian cancer mutational processes drive site-specific immune evasion

Ignacio Vázquez-Garćıa, Florian Uhlitz, Nicholas Ceglia, +58

Nature

Single-cell genomic variation induced by mutational processes in cancer

Tyler Funnell, Ciara H. O’Flanagan, Marc Williams, +115

Nature

CLK-dependent exon recognition and conjoined gene formation revealed with a novel small molecule inhibitor

Tyler Funnell, Shinya Tasaki, Arusha Oloumi, +33

Nature Communications

Systematic analysis of somatic mutations impacting gene expression in 12 tumour types

Jiarui Ding, Melissa K. McConechy, Hugo M. Horlings, +11

Nature Communications

Integrated structural variation and point mutation signatures in cancer genomes using correlated topic models

Tyler Funnell, Allen W. Zhang, Diljot Grewal, +4

PLoS Computational Biology

Structural VariationMachine LearningEngineeringGeneticsMutation Signatures +20

Cancer phylogenetic tree inference at scale from 1000s of single cell genomes

Sohrab Salehi, Fatemeh Dorri, Kevin Chern, +12

Sitka TransformationGeneticsNew GenerationGenomicsSequence Alignment +21

Cancer phylogenetic tree inference at scale from 1000s of single cell genomes

Sohrab Salehi, Fatemeh Dorri, Kevin Chern, +12

Peer Community Journal

Sitka TransformationGeneticsNew GenerationGenomicsSequence Alignment +20

Single-cell mtDNA dynamics in tumors is driven by coregulation of nuclear and mitochondrial genomes

Minsoo Kim, Alexander N. Gorelick, Ignacio Vázquez-Garćıa, +18

Nature Genetics

GeneticsGenomicsTumor BiologyMitochondrial BiogenesisTumor Heterogeneity +17

An inflammatory biomarker signature of response to CAR-T cell therapy in non-Hodgkin lymphoma

Sandeep Raj, Teng Fei, Shalev Fried, +39

Nature Medicine