James Shorter - Concepedia

Author

James Shorter

University of Pennsylvania ORCID

Also Known As

J Shorter, J. Shorter, James G Shorter, James Ng, James Shorter, Noll, Megan M., Sfakianos, Jeff, Shorter, J

282

Publications

26.6K

Citations

H-Index

107

Concepts

All Affiliations

University of Pennsylvania Howard Hughes Medical Institute Johns Hopkins University Whitehead Institute for Biomedical Research Stanford University

About

James Shorter is an author at University of Pennsylvania specializing in molecular biology, medicine, and natural sciences.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	37	51	6.8K
2	Natural Sciences	31	41	4.5K
3	Engineering	4	4	1.2K
4	Social Sciences	3	3	725
5	Health Sciences	1	1	139

James Shorter

119

Publications

14.6K

Citations

H-Index

Page 1

	Year	Citations
TDP-43 Is Intrinsically Aggregation-prone, and Amyotrophic Lateral Sclerosis-linked Mutations Accelerate Aggregation and Increase Toxicity Brian S. Johnson, David Snead, Jonathan J. Lee, Journal of Biological Chemistry Neurodegenerative DiseasesAmyotrophic Lateral SclerosisIncrease ToxicityTdp-43 AggregatesDegenerative Disease	2009	787
RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43 Jacob R. Mann, Amanda M. Gleixner, Jocelyn C. Mauna, Neuron Signal TransductionMolecular NeuroscienceRna Binding ProteinsRna BiologyMolecular Biology	2019	547
The Parkinson's disease protein α-synuclein disrupts cellular Rab homeostasis Aaron D. Gitler, Brooke J. Bevis, James Shorter, Proceedings of the National Academy of Sciences Alpha-syn PathobiologyAlpha-syn ToxicitySynaptic SignalingAutophagyEndocytic Pathway	2007	537
TDP-43 represses cryptic exon inclusion in the FTD–ALS gene UNC13A X. Rosa, Mercedes Prudencio, Yuka Koike, Nature	2022	520
Cytoplasmic TDP-43 De-mixing Independent of Stress Granules Drives Inhibition of Nuclear Import, Loss of Nuclear TDP-43, and Cell Death F. Gasset-Rosa, Shan Lu, Haiyang Yu, Neuron Nuclear ImportCell RegulationMedicineApoptosisCell Death	2019	499
Hsp104 Catalyzes Formation and Elimination of Self-Replicating Sup35 Prion Conformers James Shorter, Susan Lindquist Science EngineeringProtein AssemblyMolecular BiologyHigher Hsp104 ConcentrationsInsufficient Hsp104	2004	472
Nuclear-Import Receptors Reverse Aberrant Phase Transitions of RNA-Binding Proteins with Prion-like Domains Lin Guo, Hong Joo Kim, Hejia Wang, Cell Natural SciencesRna Binding ProteinsRna Structure PredictionRna BiologyMolecular Biology	2018	467
A complex of mammalian Ufd1 and Npl4 links the AAA-ATPase, p97, to ubiquitin and nuclear transport pathways Hemmo Meyer, James Shorter, Joachim Seemann, The EMBO Journal Mammalian Ufd1Protein FunctionSignal TransductionMolecular PathwayNuclear Transport Pathways	2000	442
Poly(ADP-Ribose) Prevents Pathological Phase Separation of TDP-43 by Promoting Liquid Demixing and Stress Granule Localization Leeanne McGurk, Edward Gomes, Lin Guo, Molecular Cell EngineeringPolymer ScienceStress Granule LocalizationLiquid DemixingMolecular Biology	2018	410
A yeast functional screen predicts new candidate ALS disease genes Julien Couthouis, Michael P. Hart, James Shorter, Proceedings of the National Academy of Sciences	2011	394

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