Aaron D. Gitler

α-Synuclein Blocks ER-Golgi Traffic and Rab1 Rescues Neuron Loss in Parkinson's Models

Antony A. Cooper, Aaron D. Gitler, Anil G. Cashikar et al. · Science · 2006 · 1.4K citations · Full text

Synaptic Transmission, Molecular Biology, Yeast Cells +18

Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS

Andrew C. Elden, Hyung Jun Kim, Michael P. Hart et al. · Nature · 2010 · 1.3K citations

Neurodegenerative Diseases, Amyotrophic Lateral Sclerosis, Molecular Neuroscience +6

Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways

Elizabeth T. Cirulli, Brittany N. Lasseigne, Slavé Petrovski et al. · Science · 2015 · 972 citations · Full text

Engineering, Exome Sequencing, Genetics +18

TDP-43 Is Intrinsically Aggregation-prone, and Amyotrophic Lateral Sclerosis-linked Mutations Accelerate Aggregation and Increase Toxicity

Brian S. Johnson, David Snead, Jonathan J. Lee et al. · Journal of Biological Chemistry · 2009 · 787 citations · Full text

Neurodegenerative Diseases, Amyotrophic Lateral Sclerosis, Increase Toxicity +10

Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS

Ana Jovičić, Jérôme Mertens, Steven Boeynaems et al. · Nature Neuroscience · 2015 · 616 citations · Full text

Nucleocytoplasmic Transport Defects, Amyotrophic Lateral Sclerosis, Biochemistry +4