Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS

Ubiquitinated TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis

Manuela Neumann, Deepak M. Sampathu, Linda K. Kwong et al. · Science · 2006 · 6.5K citations

α-Synuclein Blocks ER-Golgi Traffic and Rab1 Rescues Neuron Loss in Parkinson's Models

Antony A. Cooper, Aaron D. Gitler, Anil G. Cashikar et al. · Science · 2006 · 1.4K citations · Full text

Synaptic Transmission, Molecular Biology, Yeast Cells +18

Chaperone Suppression of α-Synuclein Toxicity in a <i>Drosophila</i> Model for Parkinson's Disease

Pavan K. Auluck, Ho Yin Edwin Chan, John Q. Trojanowski et al. · Science · 2002 · 1.2K citations

Drosophila Melanogaster, Neurodegenerative Diseases, Mitophagy +14

Moderate expansion of a normally biallelic trinucleotide repeat in spinocerebellar ataxia type 2

Stefan-M. Pulst, Alex Nechiporuk, Tamilla Nechiporuk et al. · Nature Genetics · 1996 · 1.1K citations

Molecular Neuroscience, Genetic Disorder, Medicine +6

Cloning of the gene for spinocerebellar ataxia 2 reveals a locus with high sensitivity to expanded CAG/glutamine repeats

Georges Imbert, Frédéric Saudou, Gaël Yvert et al. · Nature Genetics · 1996 · 846 citations

Molecular Neuroscience, Spinocerebellar Ataxia 2, High Sensitivity +11