Mark Stubbs

A selective chemical probe for exploring the role of CDK8 and CDK19 in human disease

Trevor Dale, Paul A. Clarke, Christina Esdar et al. · Nature Chemical Biology · 2015 · 139 citations · Full text

Molecular Immunology, Signal Transduction, Receptor Tyrosine Kinase +7

Exploiting evolutionary steering to induce collateral drug sensitivity in cancer

Ahmet Acar, Daniel Nichol, Javier Fernández-Mateos et al. · Nature Communications · 2020 · 124 citations · Full text

MIR21 Drives Resistance to Heat Shock Protein 90 Inhibition in Cholangiocarcinoma

Andrea Lampis, Pietro Carotenuto, Georgios Vlachogiannis et al. · Gastroenterology · 2017 · 111 citations · Full text

Discovery of Potent, Selective, and Orally Bioavailable Small-Molecule Modulators of the Mediator Complex-Associated Kinases CDK8 and CDK19

Aurélie Mallinger, Kai Schiemann, Christian Rink et al. · Journal of Medicinal Chemistry · 2016 · 110 citations · Full text

Vivo Metabolic Clearance, Medicinal Chemistry, Signaling Pathway +18

A Useful Approach to Identify Novel Small-Molecule Inhibitors of Wnt-Dependent Transcription

Kenneth Ewan, Bożena Pająk, Mark Stubbs et al. · Cancer Research · 2010 · 103 citations · Full text