Javier Fernández-Mateos

Patient-derived organoids model treatment response of metastatic gastrointestinal cancers

Georgios Vlachogiannis, Somaieh Hedayat, Alexandra Vatsiou et al. · Science · 2018 · 2.1K citations · Full text

Medicine, Oncology, Pharmacology +17

Longitudinal Liquid Biopsy and Mathematical Modeling of Clonal Evolution Forecast Time to Treatment Failure in the PROSPECT-C Phase II Colorectal Cancer Clinical Trial

Khurum Khan, David Cunningham, Benjamin Werner et al. · Cancer Discovery · 2018 · 237 citations · Full text

Medicine, Molecular Biology, Oncology +17

Phenotypic plasticity and genetic control in colorectal cancer evolution

Jacob Househam, Timon Heide, George D. Cresswell et al. · Nature · 2022 · 182 citations · Full text

Medicine, Evolutionary Biology, Genetics +17

Exploiting evolutionary steering to induce collateral drug sensitivity in cancer

Ahmet Acar, Daniel Nichol, Javier Fernández-Mateos et al. · Nature Communications · 2020 · 128 citations · Full text

Medicine, Evolutionary Biology, Oncology +17

The co-evolution of the genome and epigenome in colorectal cancer

Timon Heide, Jacob Househam, George D. Cresswell et al. · Nature · 2022 · 125 citations · Full text

Medicine, Genetics, Oncology +17