Javier Fernández-Mateos

Patient-derived organoids model treatment response of metastatic gastrointestinal cancers

Georgios Vlachogiannis, Somaieh Hedayat, Alexandra Vatsiou et al. · Science · 2018 · 1.9K citations · Full text

Longitudinal Liquid Biopsy and Mathematical Modeling of Clonal Evolution Forecast Time to Treatment Failure in the PROSPECT-C Phase II Colorectal Cancer Clinical Trial

Khurum Khan, David Cunningham, Benjamin Werner et al. · Cancer Discovery · 2018 · 233 citations · Full text

Phenotypic plasticity and genetic control in colorectal cancer evolution

Jacob Househam, Timon Heide, George D. Cresswell et al. · Nature · 2022 · 168 citations · Full text

Exploiting evolutionary steering to induce collateral drug sensitivity in cancer

Ahmet Acar, Daniel Nichol, Javier Fernández-Mateos et al. · Nature Communications · 2020 · 124 citations · Full text

The co-evolution of the genome and epigenome in colorectal cancer

Timon Heide, Jacob Househam, George D. Cresswell et al. · Nature · 2022 · 118 citations · Full text