Ahmet Acar

Autocrine TGF-β and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts

Yasushi Kojima, Ahmet Acar, Elinor Ng Eaton et al. · Proceedings of the National Academy of Sciences · 2010 · 830 citations · Full text

Medicine, Cancer Biology, Oncology +17

Anti-estrogen Resistance in Human Breast Tumors Is Driven by JAG1-NOTCH4-Dependent Cancer Stem Cell Activity

Bruno M. Simões, Ciara O’Brien, Rachel Eyre et al. · Cell Reports · 2015 · 197 citations · Full text

Medicine, Cancer Biology, Oncology +17

Subclonal reconstruction of tumors by using machine learning and population genetics

Giulio Caravagna, Timon Heide, Marc Williams et al. · Nature Genetics · 2020 · 134 citations · Full text

Life Sciences, Genetics, Oncology +16

Exploiting evolutionary steering to induce collateral drug sensitivity in cancer

Ahmet Acar, Daniel Nichol, Javier Fernández-Mateos et al. · Nature Communications · 2020 · 128 citations · Full text

Medicine, Evolutionary Biology, Oncology +17

TGF-beta receptor type-2 expression in cancer-associated fibroblasts regulates breast cancer cell growth and survival and is a prognostic marker in pre-menopausal breast cancer

Susann Busch, Ahmet Acar, Ylva Magnusson et al. · Oncogene · 2013 · 123 citations

Medicine, Cancer Biology, Oncology +12