Ahmet Acar

Autocrine TGF-β and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts

Yasushi Kojima, Ahmet Acar, Elinor Ng Eaton et al. · Proceedings of the National Academy of Sciences · 2010 · 812 citations · Full text

Breast Oncology, Autocrine-signaling Loops Initiate, Cancer Biology +17

Anti-estrogen Resistance in Human Breast Tumors Is Driven by JAG1-NOTCH4-Dependent Cancer Stem Cell Activity

Bruno M. Simões, Ciara O’Brien, Rachel Eyre et al. · Cell Reports · 2015 · 194 citations · Full text

Subclonal reconstruction of tumors by using machine learning and population genetics

Giulio Caravagna, Timon Heide, Marc Williams et al. · Nature Genetics · 2020 · 127 citations · Full text

Radiation Oncology, Engineering, Machine Learning +9

Exploiting evolutionary steering to induce collateral drug sensitivity in cancer

Ahmet Acar, Daniel Nichol, Javier Fernández-Mateos et al. · Nature Communications · 2020 · 124 citations · Full text

TGF-beta receptor type-2 expression in cancer-associated fibroblasts regulates breast cancer cell growth and survival and is a prognostic marker in pre-menopausal breast cancer

Susann Busch, Ahmet Acar, Ylva Magnusson et al. · Oncogene · 2013 · 121 citations

Prognostic Marker, Breast Oncology, Oncology +10