Bruno M. Simões

Sox2 promotes tamoxifen resistance in breast cancer cells

Marco Piva, Giacomo Domenici, Oihana Iriondo et al. · EMBO Molecular Medicine · 2013 · 340 citations · Full text

Targeting CXCR1/2 Significantly Reduces Breast Cancer Stem Cell Activity and Increases the Efficacy of Inhibiting HER2 via HER2-Dependent and -Independent Mechanisms

Jagdeep Singh, Gillian Farnie, Nigel Bundred et al. · Clinical Cancer Research · 2012 · 209 citations · Full text

Anti-estrogen Resistance in Human Breast Tumors Is Driven by JAG1-NOTCH4-Dependent Cancer Stem Cell Activity

Bruno M. Simões, Ciara O’Brien, Rachel Eyre et al. · Cell Reports · 2015 · 194 citations · Full text

A Sox2–Sox9 signalling axis maintains human breast luminal progenitor and breast cancer stem cells

Giacomo Domenici, Iskander Aurrekoetxea-Rodríguez, Bruno M. Simões et al. · Oncogene · 2019 · 151 citations · Full text

Microenvironmental IL1β promotes breast cancer metastatic colonisation in the bone via activation of Wnt signalling

Rachel Eyre, Denis Alférez, Angélica Santiago-Gómez et al. · Nature Communications · 2019 · 139 citations · Full text