Concepedia
Statistics
Publications
11
Citations
787
H-Index
Active since
2008
Affiliations
University of Manchester(Current)
AstraZeneca (United Kingdom)
Cancer Research UK Manchester Institute
Edinburgh Cancer Research
The Christie NHS Foundation Trust
Denis Alférez is an author at University of Manchester specializing in tumor biology, cell biology, and medicine.
Top concepts
MedicineOncologyCell BiologyPharmacologyTumor BiologyApoptosisPathologyCell DeathCancer BiologyCancer Research
Publications per year
2008–2023
Anti-estrogen Resistance in Human Breast Tumors Is Driven by JAG1-NOTCH4-Dependent Cancer Stem Cell Activity
Bruno M. Simões, Ciara O’Brien, Rachel Eyre et al. · Cell Reports · 2015 · 194 citations · Full text
Microenvironmental IL1β promotes breast cancer metastatic colonisation in the bone via activation of Wnt signalling
Rachel Eyre, Denis Alférez, Angélica Santiago-Gómez et al. · Nature Communications · 2019 · 139 citations · Full text
The MEK1/2 inhibitor, selumetinib (AZD6244; ARRY-142886), enhances anti-tumour efficacy when combined with conventional chemotherapeutic agents in human tumour xenograft models
Sarah V. Holt, Armelle Logié, Rajesh Odedra et al. · British Journal of Cancer · 2012 · 111 citations · Full text
Enhanced Apoptosis and Tumor Growth Suppression Elicited by Combination of MEK (Selumetinib) and mTOR Kinase Inhibitors (AZD8055)
Sarah V. Holt, Armelle Logié, Barry R. Davies et al. · Cancer Research · 2012 · 83 citations
Dual Mtorc1, Mtor Kinase Inhibitors, Medicine +12
Patient-derived Mammosphere and Xenograft Tumour Initiation Correlates with Progression to Metastasis
Rachel Eyre, Denis Alférez, Katherine Spence et al. · Journal of Mammary Gland Biology and Neoplasia · 2016 · 51 citations · Full text
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