Concepedia

Denis Alférez

DA

11

Publications

787

Citations

11

H-Index

2008

Active since

Affiliations

University of Manchester(Current)

AstraZeneca (United Kingdom)

Cancer Research UK Manchester Institute

Edinburgh Cancer Research

The Christie NHS Foundation Trust

Denis Alférez is an author at University of Manchester specializing in tumor biology, cell biology, and medicine.

ORCID

Top concepts

Publications per year

2008–2023

11

Publications

11

Anti-estrogen Resistance in Human Breast Tumors Is Driven by JAG1-NOTCH4-Dependent Cancer Stem Cell Activity

Bruno M. Simões, Ciara O’Brien, Rachel Eyre et al. · Cell Reports · 2015 · 194 citations · Full text

Microenvironmental IL1β promotes breast cancer metastatic colonisation in the bone via activation of Wnt signalling

Rachel Eyre, Denis Alférez, Angélica Santiago-Gómez et al. · Nature Communications · 2019 · 139 citations · Full text

The MEK1/2 inhibitor, selumetinib (AZD6244; ARRY-142886), enhances anti-tumour efficacy when combined with conventional chemotherapeutic agents in human tumour xenograft models

Sarah V. Holt, Armelle Logié, Rajesh Odedra et al. · British Journal of Cancer · 2012 · 111 citations · Full text

Enhanced Apoptosis and Tumor Growth Suppression Elicited by Combination of MEK (Selumetinib) and mTOR Kinase Inhibitors (AZD8055)

Sarah V. Holt, Armelle Logié, Barry R. Davies et al. · Cancer Research · 2012 · 83 citations

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Patient-derived Mammosphere and Xenograft Tumour Initiation Correlates with Progression to Metastasis

Rachel Eyre, Denis Alférez, Katherine Spence et al. · Journal of Mammary Gland Biology and Neoplasia · 2016 · 51 citations · Full text

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