Sarah V. Holt

Bub1 is required for kinetochore localization of BubR1, Cenp-E, Cenp-F and Mad2, and chromosome congression

Victoria Johnson, Maria I. F. Scott, Sarah V. Holt et al. · Journal of Cell Science · 2004 · 343 citations

Life Sciences, Cell Biology, Molecular Biology +17

The MEK1/2 inhibitor, selumetinib (AZD6244; ARRY-142886), enhances anti-tumour efficacy when combined with conventional chemotherapeutic agents in human tumour xenograft models

Sarah V. Holt, Armelle Logié, Rajesh Odedra et al. · British Journal of Cancer · 2012 · 111 citations · Full text

Medicine, Oncology, Pharmacology +16

Silencing Cenp-F weakens centromeric cohesion, prevents chromosome alignment and activates the spindle checkpoint

Sarah V. Holt, M. Vergnolle, Deema Hussein et al. · Journal of Cell Science · 2005 · 107 citations

Life Sciences, Cell Biology, Molecular Biology +17

Enhanced Apoptosis and Tumor Growth Suppression Elicited by Combination of MEK (Selumetinib) and mTOR Kinase Inhibitors (AZD8055)

Sarah V. Holt, Armelle Logié, Barry R. Davies et al. · Cancer Research · 2012 · 86 citations

Medicine, Oncology, Pharmacology +17

The Development of an Immunohistochemical Method to Detect the Autophagy-Associated Protein LC3-II in Human Tumor Xenografts

Sarah V. Holt, Beata S. Wyspiańska, Kevin J. Randall et al. · Toxicologic Pathology · 2011 · 53 citations

Life Sciences, Molecular Biology, Oncology +17