George Tonn

The Conduct of in Vitro Studies to Address Time-Dependent Inhibition of Drug-Metabolizing Enzymes: A Perspective of the Pharmaceutical Research and Manufacturers of America

Scott Grimm, Heidi J. Einolf, Steven D. Hall et al. · Drug Metabolism and Disposition · 2009 · 304 citations

SAR and Mode of Action of Novel Non-Nucleoside Inhibitors of Hepatitis C NS5b RNA Polymerase

Jay P. Powers, Derek E. Piper, Yang Li et al. · Journal of Medicinal Chemistry · 2006 · 125 citations · Full text

Discovery and optimization of a series of quinazolinone-derived antagonists of CXCR3

Michael G. Johnson, An‐Rong Li, Jiwen Liu et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 103 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Biochemistry +8

AMG 837: A Novel GPR40/FFA1 Agonist that Enhances Insulin Secretion and Lowers Glucose Levels in Rodents

Daniel C.-H. Lin, Jane Zhang, Run Zhuang et al. · PLoS ONE · 2011 · 94 citations · Full text

<scp>DNL</scp>104, a Centrally Penetrant <scp>RIPK</scp>1 Inhibitor, Inhibits <scp>RIP</scp>1 Kinase Phosphorylation in a Randomized Phase I Ascending Dose Study in Healthy Volunteers

Hendrika W. Grievink, Jules A. A. C. Heuberger, Fen Huang et al. · Clinical Pharmacology & Therapeutics · 2019 · 70 citations · Full text