Jay P. Powers

C5a Receptor (CD88) Blockade Protects against MPO-ANCA GN

Hong Xiao, Daniel J. Dairaghi, Jay P. Powers et al. · Journal of the American Society of Nephrology · 2013 · 346 citations · Full text

Immunology, Immune Regulation, Immunologic Mechanism +21

Elucidation of CXCR7-Mediated Signaling Events and Inhibition of CXCR4-Mediated Tumor Cell Transendothelial Migration by CXCR7 Ligands

Brian A. Zabel, Yu Wang, Susanna Lewén et al. · The Journal of Immunology · 2009 · 285 citations · Full text

Cancer Research, Vitro Chemotaxis, Chemokine Biology +13

Crystal Structures of IRAK-4 Kinase in Complex with Inhibitors: A Serine/Threonine Kinase with Tyrosine as a Gatekeeper

Zhulun Wang, Jinsong Liu, Athena Sudom et al. · Structure · 2006 · 145 citations · Full text

Biochemistry, Serine/threonine Kinase, Natural Sciences +10

Characterization of Pharmacologic and Pharmacokinetic Properties of CCX168, a Potent and Selective Orally Administered Complement 5a Receptor Inhibitor, Based on Preclinical Evaluation and Randomized Phase 1 Clinical Study

Pirow Bekker, Daniel J. Dairaghi, Lisa Seitz et al. · PLoS ONE · 2016 · 144 citations · Full text

Immunology, Potent C5ar Antagonist, Receptor Inhibitor +21

SAR and Mode of Action of Novel Non-Nucleoside Inhibitors of Hepatitis C NS5b RNA Polymerase

Jay P. Powers, Derek E. Piper, Yang Li et al. · Journal of Medicinal Chemistry · 2006 · 125 citations · Full text