Jules A. A. C. Heuberger

Author

Also Known As

J. Heuberger, JULES A. A. C. HEUBERGER, Jules A A C Heuberger, Jules A. A. C. Heuberger, Jules A.A.C. Heuberger, Jules Heuberger, | Jules A. A. C. Heuberger

Publications

1.4K

Citations

H-Index

Concepts

All Affiliations

Centre for Human Drug Research Leiden University Medical Center Denali Therapeutics (United States)University of Florida Harvard University

About

Jules A. A. C. Heuberger is an author at Centre for Human Drug Research specializing in medicine, health sciences, and neurology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	5	5	219
2	Health Sciences	3	3	143
3	Natural Sciences	1	1	79
4	Applied Physiology	1	1	54
5	Biochemistry	1	1	79

Jules A. A. C. Heuberger

Publications

Citations

H-Index

Page 1

	Year	Citations
<scp>LRRK2</scp> Inhibition by <scp>BIIB122</scp> in Healthy Participants and Patients with Parkinson's Disease Danna Jennings, Sarah Huntwork‐Rodriguez, Maurits F. J. M. Vissers, Movement Disorders	2023	97
Safety, pharmacokinetics and target engagement of novel <scp>RIPK1</scp> inhibitor <scp>SAR443060</scp> (<scp>DNL747</scp>) for neurodegenerative disorders: Randomized, <scp>placebo‐controlled</scp>, <scp>double‐blind</scp> phase I/Ib studies in healthy subjects and patients Maurits F. J. M. Vissers, Jules A. A. C. Heuberger, Geert Jan Groeneveld, Clinical and Translational Science	2022	84
When is Protein Binding Important?* Jules A. A. C. Heuberger, Stephan Schmidt, Hartmut Derendorf Journal of Pharmaceutical Sciences Protein ChemistryProtein FunctionProtein AssemblyBiochemistryProtein Folding	2013	79
Effects on Spasticity and Neuropathic Pain of an Oral Formulation of Δ9-tetrahydrocannabinol in Patients With Progressive Multiple Sclerosis Guido van Amerongen, Kawita M. S. Kanhai, Anne Catrien Baakman, Clinical Therapeutics Cannabis UsePain DisordersNeurological AssessmentHealth SciencesPain Medicine	2017	78
Population Pharmacokinetic Model of THC Integrates Oral, Intravenous, and Pulmonary Dosing and Characterizes Short- and Long-term Pharmacokinetics Jules A. A. C. Heuberger, Zheng Guan, Olubukayo‐Opeyemi Oyetayo, Clinical Pharmacokinetics Population Pharmacokinetic ModelPharmacokinetic ModelingThc Integrates OralPharmacologyPulmonary Pharmacology	2014	75
<scp>DNL</scp>104, a Centrally Penetrant <scp>RIPK</scp>1 Inhibitor, Inhibits <scp>RIP</scp>1 Kinase Phosphorylation in a Randomized Phase I Ascending Dose Study in Healthy Volunteers Hendrika W. Grievink, Jules A. A. C. Heuberger, Fen Huang, Clinical Pharmacology & Therapeutics	2019	70
Accelerated Development of the Dual Orexin Receptor Antagonist ACT‐541468: Integration of a Microtracer in a First‐in‐Human Study Clemens Muehlan, Jules A. A. C. Heuberger, Pierre‐Éric Juif, Clinical Pharmacology & Therapeutics	2018	65
Effects of erythropoietin on cycling performance of well trained cyclists: a double-blind, randomised, placebo-controlled trial Jules A. A. C. Heuberger, Joris I. Rotmans, Pim Gal, The Lancet Haematology Physical ActivityKinesiologyExerciseExercise PhysiologyPhysical Exercise	2017	54
Tolerance to Opioid‐Induced Respiratory Depression in Chronic High‐Dose Opioid Users: A Model‐Based Comparison With Opioid‐Naïve Individuals Marijke Hyke Algera, Erik Olofsen, Laurence Moss, Clinical Pharmacology & Therapeutics	2020	54
EpoR stimulates rapid cycling and larger red cells during mouse and human erythropoiesis Daniel Hidalgo, Jacob Bejder, Ramona Pop, Nature Communications	2021	47

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