Wuxian Shi

The allosteric regulation of pyruvate kinase by fructose-1,6-bisphosphate

Melissa S. Jurica, Andrew D. Mesecar, Patrick J. Heath et al. · Structure · 1998 · 433 citations · Full text

Transition State Structure of Purine Nucleoside Phosphorylase and Principles of Atomic Motion in Enzymatic Catalysis^,

Wuxian Shi, Greg A. Kicska, E.V. Fedorov et al. · Biochemistry · 2000 · 190 citations

Mechanism of gasdermin D recognition by inflammatory caspases and their inhibition by a gasdermin D-derived peptide inhibitor

Jie Yang, Chuanping Wang, Rui Yang et al. · Proceedings of the National Academy of Sciences · 2018 · 174 citations · Full text

The 2.0 A structure of human hypoxanthine-guanine phosphoribosyltransferase in complex with a transition-state analog inhibitor.

Vern L. Schramm, Steven C. Almo, Wuxian Shi et al. · Nature Structural Biology · 1999 · 156 citations

Molecular Pharmacology, Cellular Enzymology, Biochemistry +10

Structure of Murine CTLA-4 and Its Role in Modulating T Cell Responsiveness

David A. Ostrov, Wuxian Shi, Jean-Claude D. Schwartz et al. · Science · 2000 · 143 citations

Crystal Structure, Adaptive Immune System, Immunology +20