Rui Yang

Crystal Structures of the Full-Length Murine and Human Gasdermin D Reveal Mechanisms of Autoinhibition, Lipid Binding, and Oligomerization

Zhonghua Liu, Chuanping Wang, Jie Yang et al. · Immunity · 2019 · 265 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Mechanism of gasdermin D recognition by inflammatory caspases and their inhibition by a gasdermin D-derived peptide inhibitor

Jie Yang, Chuanping Wang, Rui Yang et al. · Proceedings of the National Academy of Sciences · 2018 · 180 citations · Full text

Life Sciences, Cell Biology, Immunology +14

NLRP3 Promotes Glioma Cell Proliferation and Invasion via the Interleukin-1β/NF-κB p65 Signals

Liping Xue, Bin Lü, Bibo Gao et al. · Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics · 2018 · 56 citations · Full text

Life Sciences, Cancer Biology, Oncology +17

Gasdermin D restricts anti-tumor immunity during PD-L1 checkpoint blockade

Yuying Jiang, Yongbing Yang, Yingchao Hu et al. · Cell Reports · 2022 · 50 citations · Full text

Life Sciences, Immunology, Oncology +17

The Gasdermin D N-terminal fragment acts as a negative feedback system to inhibit inflammasome-mediated activation of Caspase-1/11

Yingchao Hu, Yuying Jiang, Sheng Li et al. · Proceedings of the National Academy of Sciences · 2022 · 47 citations · Full text

Life Sciences, Cell Biology, Immunology +17