Debra Yager

Enhanced Neurofibrillary Degeneration in Transgenic Mice Expressing Mutant Tau and APP

Jada Lewis, Dennis W. Dickson, Wen-Lang Lin et al. · Science · 2001 · 1.6K citations

Familial Alzheimer's Disease–Linked Presenilin 1 Variants Elevate Aβ1–42/1–40 Ratio In Vitro and In Vivo

David Borchelt, Gopal Thinakaran, Christopher B. Eckman et al. · Neuron · 1996 · 1.5K citations · Full text

Increased amyloid-β42(43) in brains of mice expressing mutant presenilin 1

Karen Duff, Chris Eckman, Cindy Zehr et al. · Nature · 1996 · 1.4K citations

Neurodegenerative Diseases, Molecular Neuroscience, Mutant Presenilin 1 +9

Substrate-targeting γ-secretase modulators

Thomas Kukar, Thomas B. Ladd, Maralyssa Bann et al. · Nature · 2008 · 275 citations · Full text

Protein Secretion, Signal Transduction, Protein Expression +5

Differential Expression of Cholesterol Hydroxylases in Alzheimer's Disease

James A. Brown, Catherine Theisler, Simone Silberman et al. · Journal of Biological Chemistry · 2004 · 267 citations · Full text