Thomas B. Ladd

Diverse compounds mimic Alzheimer disease–causing mutations by augmenting Aβ42 production

Thomas Kukar, M. Paul Murphy, Jason L. Eriksen et al. · Nature Medicine · 2005 · 278 citations

Neurodegenerative Diseases, Alzheimer's Disease, Biochemistry +12

Substrate-targeting γ-secretase modulators

Thomas Kukar, Thomas B. Ladd, Maralyssa Bann et al. · Nature · 2008 · 275 citations · Full text

Protein Secretion, Signal Transduction, Protein Expression +5

High‐affinity interactions and signal transduction between Aβ oligomers and <scp>TREM</scp> 2

Christian Lessard, Samuel L. Malnik, Yingyue Zhou et al. · EMBO Molecular Medicine · 2018 · 167 citations · Full text

Overlapping profiles of Aβ peptides in the Alzheimer's disease and pathological aging brains

Brenda D. Moore, Paramita Chakrabarty, Yona Levites et al. · Alzheimer s Research & Therapy · 2012 · 109 citations · Full text

TLR5 decoy receptor as a novel anti-amyloid therapeutic for Alzheimer’s disease

Paramita Chakrabarty, Andrew Li, Thomas B. Ladd et al. · The Journal of Experimental Medicine · 2018 · 99 citations · Full text

Immunology, Immune Regulation, Immune System +18