Chris Eckman

Correlative Memory Deficits, Aβ Elevation, and Amyloid Plaques in Transgenic Mice

Karen Hsiao, Paul F. Chapman, Steven P. Nilsen et al. · Science · 1996 · 4.2K citations

Enhanced Neurofibrillary Degeneration in Transgenic Mice Expressing Mutant Tau and APP

Jada Lewis, Dennis W. Dickson, Wen-Lang Lin et al. · Science · 2001 · 1.6K citations

Increased amyloid-β42(43) in brains of mice expressing mutant presenilin 1

Karen Duff, Chris Eckman, Cindy Zehr et al. · Nature · 1996 · 1.4K citations

Neurodegenerative Diseases, Molecular Neuroscience, Mutant Presenilin 1 +9

Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes

Leigh A. Holcomb, Marcia N. Gordon, Eileen McGowan et al. · Nature Medicine · 1998 · 1.4K citations

Neurodegenerative Diseases, Molecular Neuroscience, Alzheimer's Disease +12

SOD1 rescues cerebral endothelial dysfunction in mice overexpressing amyloid precursor protein

Costantino Iadecola, Fangyi Zhang, Kiyoshi Niwa et al. · Nature Neuroscience · 1999 · 397 citations

Alzheimer's Disease, Degenerative Pathology, Protein Misfolding +10