Ian J. Owens

The Interaction of Neuraminidase and Hemagglutinin Mutations in Influenza Virus in Resistance to 4-Guanidino-Neu5Ac2en

Tony Blick, Anjali Sahasrabudhe, Mandy McDonald et al. · Virology · 1998 · 108 citations

Viral Evolution, Medicine, Pathogenesis +7

Zanamivir Susceptibility Monitoring and Characterization of Influenza Virus Clinical Isolates Obtained during Phase II Clinical Efficacy Studies

Jacqueline M. Barnett, A. Cadman, D Gor et al. · Antimicrobial Agents and Chemotherapy · 2000 · 106 citations · Full text

Vaccination, Paired Isolates, Viral Diagnostics +11

Dimeric Zanamivir Conjugates with Various Linking Groups Are Potent, Long-Lasting Inhibitors of Influenza Neuraminidase Including H5N1 Avian Influenza

Simon J. F. Macdonald, Rachel Cameron, Derek A. Demaine et al. · Journal of Medicinal Chemistry · 2005 · 87 citations · Full text

Medicinal Chemistry, Medicine, Plaque Reduction Assays +14

Potent and Long-Acting Dimeric Inhibitors of Influenza Virus Neuraminidase Are Effective at a Once-Weekly Dosing Regimen

Simon J. F. Macdonald, Keith G. Watson, Rachel Cameron et al. · Antimicrobial Agents and Chemotherapy · 2004 · 80 citations · Full text

Medicinal Chemistry, Antiviral Compound, Medicine +12

Characterization of 2 Influenza A(H3N2) Clinical Isolates with Reduced Susceptibility to Neuraminidase Inhibitors Due to Mutations in the Hemagglutinin Gene

Yacine Abed, Anne–Marie Bourgault, Robert J. Fenton et al. · The Journal of Infectious Diseases · 2002 · 58 citations · Full text

Vaccination, Viral Evolution, Kinetic Binding Assays +15