Tony Blick

Drug design against a shifting target: a structural basis for resistance to inhibitors in a variant of influenza virus neuraminidase

Joseph Varghese, Paul W. Smith, Steven L. Sollis et al. · Structure · 1998 · 200 citations · Full text

Drug Target, Drug Design, Shifting Target +10

Mutations in a Conserved Residue in the Influenza Virus Neuraminidase Active Site Decreases Sensitivity to Neu5Ac2en-Derived Inhibitors

Jennifer L. McKimm‐Breschkin, Anjali Sahasrabudhe, Tony Blick et al. · Journal of Virology · 1998 · 184 citations · Full text

Generation and Characterization of an Influenza Virus Neuraminidase Variant with Decreased Sensitivity to the Neuraminidase-Specific Inhibitor 4-Guanidino-Neu5Ac2en

Tony Blick, Tak S. Tiong, Anjali Sahasrabudhe et al. · Virology · 1995 · 152 citations

Medicine, Drug Discovery, Antiviral Drug Development +6

Generation and characterization of variants of NWS/G70C influenza virus after in vitro passage in 4-amino-Neu5Ac2en and 4-guanidino-Neu5Ac2en

Jennifer L. McKimm‐Breschkin, Tony Blick, Anjali Sahasrabudhe et al. · Antimicrobial Agents and Chemotherapy · 1996 · 152 citations · Full text

Amino Acids, Molecular Biology, Cell Culture +16

Antisense-Mediated Suppression of Hyaluronan Synthase 2 Inhibits the Tumorigenesis and Progression of Breast Cancer

Lishanthi Udabage, Gary R. Brownlee, Mark Waltham et al. · Cancer Research · 2005 · 127 citations · Full text

Tumor Biology, Hyaluronan Metabolism, Breast Oncology +14