Robert J. Fenton

Dihydropyrancarboxamides Related to Zanamivir:  A New Series of Inhibitors of Influenza Virus Sialidases. 1. Discovery, Synthesis, Biological Activity, and Structure−Activity Relationships of 4-Guanidino- and 4-Amino-4<i>H</i>-pyran-6-carboxamides

Paul W. Smith, Steven L. Sollis, Peter D. Howes et al. · Journal of Medicinal Chemistry · 1998 · 339 citations · Full text

Greater Inhibitory Activity, New Series, Antiviral Drug +16

The Interaction of Neuraminidase and Hemagglutinin Mutations in Influenza Virus in Resistance to 4-Guanidino-Neu5Ac2en

Tony Blick, Anjali Sahasrabudhe, Mandy McDonald et al. · Virology · 1998 · 108 citations

Viral Evolution, Medicine, Pathogenesis +7

Zanamivir Susceptibility Monitoring and Characterization of Influenza Virus Clinical Isolates Obtained during Phase II Clinical Efficacy Studies

Jacqueline M. Barnett, A. Cadman, D Gor et al. · Antimicrobial Agents and Chemotherapy · 2000 · 106 citations · Full text

Vaccination, Paired Isolates, Viral Diagnostics +11

Development of a GB Virus B Marmoset Model and Its Validation with a Novel Series of Hepatitis C Virus NS3 Protease Inhibitors

Helen Bright, Anthony R. Carroll, Paul Watts et al. · Journal of Virology · 2004 · 87 citations · Full text

Surrogate Animal Model, Viral Replication, Molecular Virology +15

Predicting the <i>in Vivo</i> Mechanism of Action for Drug Leads Using NMR Metabolomics

Steven Halouska, Robert J. Fenton, Raúl G. Barletta et al. · ACS Chemical Biology · 2011 · 80 citations · Full text

Drug Target, Metabolomic Profiling, Drug Resistance +19