Attilla Ting

Crystal Structures of Human ADAMTS-1 Reveal a Conserved Catalytic Domain and a Disintegrin-like Domain with a Fold Homologous to Cysteine-Rich Domains

S. Gerhardt, G. Hassall, Paul Hawtin et al. · Journal of Molecular Biology · 2007 · 97 citations

Life Sciences, Biochemistry, Molecular Biology +8

The PARP Inhibitor AZD2461 Provides Insights into the Role of PARP3 Inhibition for Both Synthetic Lethality and Tolerability with Chemotherapy in Preclinical Models

Lenka Oplustil O’Connor, Stuart L. Rulten, Aaron Cranston et al. · Cancer Research · 2016 · 92 citations

Medicine, Oncology, Pharmacology +16

Learning Medicinal Chemistry Absorption, Distribution, Metabolism, Excretion, and Toxicity (ADMET) Rules from Cross-Company Matched Molecular Pairs Analysis (MMPA)

Christian Krämer, Attilla Ting, Hao Zheng et al. · Journal of Medicinal Chemistry · 2017 · 84 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

The Discovery of 7-Methyl-2-[(7-methyl[1,2,4]triazolo[1,5-<i>a</i>]pyridin-6-yl)amino]-9-(tetrahydro-2<i>H</i>-pyran-4-yl)-7,9-dihydro-8<i>H</i>-purin-8-one (AZD7648), a Potent and Selective DNA-Dependent Protein Kinase (DNA-PK) Inhibitor

Frederick W. Goldberg, M. Raymond V. Finlay, Attilla Ting et al. · Journal of Medicinal Chemistry · 2019 · 79 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Discovery of Clinical Candidate AZD0095, a Selective Inhibitor of Monocarboxylate Transporter 4 (MCT4) for Oncology

Frederick W. Goldberg, Jason G. Kettle, Gillian M. Lamont et al. · Journal of Medicinal Chemistry · 2022 · 56 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +10