Aaron Cranston - Concepedia

Author

Aaron Cranston

Also Known As

A Cranston, A N Cranston, A. CRANSTON, A. Cranston, A. N. Cranston, A.N. Cranston, Aaron Cranston, Aaron N Cranston, Aaron N. Cranston, Glen Clack

Publications

3.7K

Citations

H-Index

Concepts

All Affiliations

University of Cambridge Cancer Research UK GW Pharmaceuticals (United Kingdom)Fondazione IRCCS Istituto Nazionale dei Tumori Sidney Kimmel Cancer Center

About

Aaron Cranston is an author at University of Cambridge specializing in medicine, cell biology, and tumor biology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	13	13	2.3K
2	Health Sciences	1	1	90
3	Natural Sciences	1	1	572
4	Public Health	1	1	70
5	Biochemistry	1	1	572

Aaron Cranston

Publications

3.3K

Citations

H-Index

Page 1

	Year	Citations
High sensitivity of BRCA1-deficient mammary tumors to the PARP inhibitor AZD2281 alone and in combination with platinum drugs Sven Rottenberg, Janneke E. Jaspers, Ariena Kersbergen, Proceedings of the National Academy of Sciences Breast OncologyPathologyCancer BiologyPlatinum DrugsTumor Biology	2008	943
4-[3-(4-Cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorobenzyl]-2<i>H</i>-phthalazin-1-one: A Novel Bioavailable Inhibitor of Poly(ADP-ribose) Polymerase-1 Keith Menear, Claire Adcock, Robert Boulter, Journal of Medicinal Chemistry Medicinal ChemistryPolymerase ActivationOral BioavailabilityPharmaceutical ScienceBiochemistry	2008	572
Loss of 53BP1 Causes PARP Inhibitor Resistance in <i>Brca1</i> -Mutated Mouse Mammary Tumors Janneke E. Jaspers, Ariena Kersbergen, Ute Boon, Cancer Discovery	2012	510
Increased Hypermutation at G and C Nucleotides in Immunoglobulin Variable Genes from Mice Deficient in the MSH2 Mismatch Repair Protein Quy H. Phung, David B. Winter, Aaron Cranston, The Journal of Experimental Medicine	1998	182
Apoptosis induced by overexpression of hMSH2 or hMLH1. Hong Zhang, Burt T. Richards, Teresa Wilson, PubMed Hpms2 Induces ApoptosisRedox SignalingGenome InstabilityHmlh1 DeficiencySomatic Variant	1999	179
Poly(ADP-Ribose) Polymerase-1 Inhibitor Treatment Regresses Autochthonous <i>Brca2/p53</i> -Mutant Mammary Tumors <i>In vivo</i> and Delays Tumor Relapse in Combination with Carboplatin Trevor Hay, James R. Matthews, Lucie Pietzka, Cancer Research	2009	110
Isolation and mapping of a human septin gene to a region on chromosome 17q, commonly deleted in sporadic epithelial ovarian tumors. S.E. Hilary Russell, Michael A. McIlhatton, James F. Burrows, PubMed CytogeneticsGeneticsGynecologyPathologyMolecular Genetics	2000	102
The PARP Inhibitor AZD2461 Provides Insights into the Role of PARP3 Inhibition for Both Synthetic Lethality and Tolerability with Chemotherapy in Preclinical Models Lenka Oplustil O’Connor, Stuart L. Rulten, Aaron Cranston, Cancer Research Chemoprevention StrategyParp3 InhibitionPharmacotherapyCancer BiologyTumor Biology	2016	90
Severe Attenuation of the B Cell Immune Response in Msh2-deficient Mice Kalpit A. Vora, Kathleen M. Tumas-Brundage, Vicky M. Lentz, The Journal of Experimental Medicine	1999	83
RET Is Constitutively Activated by Novel Tandem Mutations that Alter the Active Site Resulting in Multiple Endocrine Neoplasia Type 2B Aaron Cranston, Cristiana Carniti, Kim Oakhill, Cancer Research Novel Tandem MutationsSystems BiologySignal TransductionSomatic VariantReceptor Tyrosine Kinase	2006	83

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