Concepedia

Duncan S. Holmes

DS

40

Publications

1.4K

Citations

23

H-Index

1988

Active since

Affiliations

GlaxoSmithKline (United Kingdom)(Current)

GlaxoSmithKline (France)

GlaxoSmithKline (United States)

University of Southampton

University of Edinburgh

Duncan S. Holmes is an author at GlaxoSmithKline (United Kingdom) specializing in medicine, pharmacology, and biochemistry.

ORCID

Top concepts

Publications per year

1988–2021

40

Publications

40

Kynurenine-3-monooxygenase inhibition prevents multiple organ failure in rodent models of acute pancreatitis

Damian J. Mole, Scott P. Webster, Iain Uings et al. · Nature Medicine · 2016 · 155 citations · Full text

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Synthesis and Structure−Activity Relationships of Long-acting β<sub>2</sub>Adrenergic Receptor Agonists Incorporating Metabolic Inactivation: An Antedrug Approach

Panayiotis A. Procopiou, Victoria J. Barrett, Nicola Bevan et al. · Journal of Medicinal Chemistry · 2010 · 98 citations · Full text

Chemoselective Glycosylations. 2. Differences in Size of Anomeric Leaving Groups Can Be Exploited in Chemoselective Glycosylations

Richard Geurtsen, Duncan S. Holmes, Geert‐Jan Boons · The Journal of Organic Chemistry · 1997 · 79 citations

, , +18

Biphenyl amide p38 kinase inhibitors 3: Improvement of cellular and in vivo activity

Richard Angell, Paul Bamborough, Jacky B. Buckton et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 72 citations · Full text

, , +11

Development of a small molecule that corrects misfolding and increases secretion of Z α <sub>1</sub> ‐antitrypsin

David A. Lomas, James A. Irving, Christopher C. Arico-Muendel et al. · EMBO Molecular Medicine · 2021 · 62 citations · Full text

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