David A. Lomas

Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells

Kosuke Yusa, S. Tamir Rashid, Hélène Strick‐Marchand et al. · Nature · 2011 · 638 citations · Full text

α1-Antitrypsin Deficiency, Induced Pluripotent Stem Cell, Medicine +7

Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells

S. Tamir Rashid, Sébastien Corbineau, Stefan J. Marciniak et al. · Journal of Clinical Investigation · 2010 · 588 citations · Full text

Metabolic Disorders, Fatty Liver Disease, Metabolic Syndrome +20

Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations

Phuwanat Sakornsakolpat, Dmitry Prokopenko, Maxime Lamontagne et al. · Nature Genetics · 2019 · 407 citations · Full text

Genome-wide Association Study, Genetic Landscape, Genotype-phenotype Association +8

Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK: a prospective observational study

Rachael A Evans, Olivia C. Leavy, Matthew Richardson et al. · The Lancet Respiratory Medicine · 2022 · 407 citations · Full text

Familial dementia caused by polymerization of mutant neuroserpin

Richard L. Davis, Antony E. Shrimpton, P D Holohan et al. · Nature · 1999 · 347 citations · Full text

Alzheimer's Disease, Dementia, Frontotemporal Dementia +6