Emilie A. Chapeau

Neuronal Shp2 tyrosine phosphatase controls energy balance and metabolism

Eric Erquan Zhang, Emilie A. Chapeau, Kazuki Hagihara et al. · Proceedings of the National Academy of Sciences · 2004 · 261 citations

Life Sciences, Neurobiology, Neuroscience +15

Direct and selective pharmacological disruption of the YAP–TEAD interface by IAG933 inhibits Hippo-dependent and RAS–MAPK-altered cancers

Emilie A. Chapeau, Laurent Sansregret, Giorgio Giacomo Galli et al. · Nature Cancer · 2024 · 132 citations · Full text

Medicine, Cancer Biology, Oncology +15

Dose and Schedule Determine Distinct Molecular Mechanisms Underlying the Efficacy of the p53–MDM2 Inhibitor HDM201

Sébastien Jeay, Stéphane Ferretti, Philipp Holzer et al. · Cancer Research · 2018 · 87 citations · Full text

Medicine, Oncology, Pharmacology +17

Resistance mechanisms to TP53-MDM2 inhibition identified by in vivo piggyBac transposon mutagenesis screen in an Arf ^−/− mouse model

Emilie A. Chapeau, Agnieszka Gembarska, Éric Durand et al. · Proceedings of the National Academy of Sciences · 2017 · 64 citations · Full text

Medicine, Cancer Biology, Oncology +17

The First Class of Small Molecules Potently Disrupting the YAP‐TEAD Interaction by Direct Competition

Pascal Furet, Vincent Bordas, Mickaël Le Douget et al. · ChemMedChem · 2022 · 43 citations

Medicine, Oncology, Pharmacology +17