Xiaoyang Dong

Discovery of a First-in-Class Receptor Interacting Protein 1 (RIP1) Kinase Specific Clinical Candidate (GSK2982772) for the Treatment of Inflammatory Diseases

Philip A. Harris, Scott B. Berger, Jae Uk Jeong et al. · Journal of Medicinal Chemistry · 2017 · 464 citations · Full text

Drug Target, Immunology, Cell Death +22

A general asymmetric copper-catalysed Sonogashira C(sp3)–C(sp) coupling

Xiaoyang Dong, Yufeng Zhang, Canliang Ma et al. · Nature Chemistry · 2019 · 296 citations

Organometallic Catalysis, Cross-coupling Reaction, Catalysis +1

A Dual-Catalytic Strategy To Direct Asymmetric Radical Aminotrifluoromethylation of Alkenes

Jin‐Shun Lin, Xiaoyang Dong, Taotao Li et al. · Journal of the American Chemical Society · 2016 · 281 citations

Excellent Enantioselectivity, Medicinal Chemistry, Cross-coupling Reaction +15

DNA-Encoded Library Screening Identifies Benzo[<i>b</i>][1,4]oxazepin-4-ones as Highly Potent and Monoselective Receptor Interacting Protein 1 Kinase Inhibitors

Philip A. Harris, Bryan W. King, Deepak Bandyopadhyay et al. · Journal of Medicinal Chemistry · 2016 · 268 citations · Full text

Drug Target, Immunology, Kinase Inhibitors +17

Copper‐Catalyzed Asymmetric Coupling of Allenyl Radicals with Terminal Alkynes to Access Tetrasubstituted Allenes

Xiaoyang Dong, Tian‐Ya Zhan, Shengpeng Jiang et al. · Angewandte Chemie International Edition · 2020 · 162 citations

Cross-coupling Reaction, Engineering, Central Chirality +14